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Organic compounds that contain an aromatic ring with one or more hydrogen atoms replaced by a halogen atom; also known as haloarene or halogenoarene. Halogen atoms include bromine, chlorine, fluorine, iodine.
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7-iodo-2',3'-dideoxy-7-deaza-guanosine is an iodinated dideoxynucleoside used as a chain-terminating nucleotide in DNA synthesis and sequencing reactions. It is supplied as a solid and is also available as a 10 mM solution in DMSO; analytical purity is listed at 99.17%.
used as a chain terminator in DNA synthesis and sequencing
available as a solid and as a 10 mM solution in DMSO
high analytical purity suitable for research applications
molecular weight 376.15 g/mol and formula C11H13IN4O3
CAS number 114748-67-3
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4-iodo-SAHA (CAS 1219807-87-0) is a hydrophobic analog of suberoylanilide hydroxamic acid (SAHA) that functions as a histone deacetylase (HDAC) inhibitor targeting both class I and II HDACs By blocking HDAC activity 4-iodo-SAHA modulates the reversible acetylation of lysine residues on histone and non-histone proteins affecting transcriptional regulation In cellular assays 4-iodo-SAHA demonstrated antiproliferative effects with EC50 values of 1 1 M in SKBR3 breast cancer cells and 0 95 0 12 0 24 0 85 and 1 3 M in HT29 U937 JA16 HL60 and K562 tumor cell lines respectively Notably it exhibited greater potency than SAHA in inhibiting proliferation of U937 leukemia cells These properties make 4-iodo-SAHA valuable for investigating HDAC-related cellular processes and cancer models
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1H-Pyrazole-4-carboxaldehyde, 3-iodo-1-(tetrahydro-2H-pyran-2-yl)- is an off-white to light yellow solid. It has a molecular weight of 306.10 and a purity of 99.83%. This chemical is designed for research use.
Off-white to light yellow solid appearance
Purity of 99.83%
Store at -20°C, protect from light, stored under nitrogen
For research use only
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